CKD MN
Conditions
Sponsors
Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosed as primary membranous nephropathy by renal biopsy and clinical examination; 2. Aged 18-75 years old; 3. CKD30ml/min), 24-hour urine protein quantitative >=1g;
Exclusion criteria
Exclusion criteria: 1. Rapidly progressive membranous nephropathy (progressive decline in renal function, necrotizing capillary vasculitis and >50% large crescent formation on renal biopsy); 2. Membranous nephropathy with IgA nephropathy; 3. Have received immunosuppressive drugs or cytotoxic drugs for more than 4 weeks in the past 6 months; 4. Have received glucocorticoids (prednisone or prednisone) at a dose of more than 20 mg/d for more than 4 weeks in the past 6 months; 5. Combined with life-threatening complications such as severe infection; 6. Those with positive HBV serological indicators other than HbsAb and those with abnormal transaminase in continuous liver function tests; 7. Patients with malignant tumors or patients with malignant tumor history, history of HIV infection, history of mental illness, acute central nervous system disease, severe gastrointestinal disease, and patients who are prohibited from using immunosuppressive agents; 8. Abnormal glucose metabolism, fasting blood sugar exceeding 6.2mmol/L; 9. Pregnant or lactating women; 10. Undergoing other clinical trial research; 11. Combined with serious diseases and dysfunction of other organs; 12. Taking probiotics for treatment in the past month; 13. The blood pressure of hypertension is controlled at 130/80mmHg.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ALB;24hupro;Scr; | — |
Countries
China
Contacts
Public ContactWANG LIN
Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed