Preeclampsia
Conditions
Interventions
Sponsors
Shenzhen Luohu People's Hospital (The Third Affiliated Hospital of Shenzhen University)
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Singleton pregnancy; 2. Subjects who are 12-20 weeks pregnant; 3. The subjects who signed the informed consent form for clinical research; 4. High risk population of preeclampsia. Evaluation index: Has one or more of the following risk factors: History of preeclampsia; diabetes; Chronic hypertension; Chronic kidney disease; SLE or antiphospholipid antibody syndrome. Or with the following > = 2 risk factors: Primipara; BMI > 30kg / m2 before pregnancy,; The age of pregnant women was 35 years old; More than 10 years from the last pregnancy; The mother or sister had a history of preeclampsia; Previous pregnancies were smaller than gestational age infants; History of placental abruption; Family history of hypertension.
Exclusion criteria
Exclusion criteria: 1. Patients allergic to aspirin or Zishenyutai pills; 2. Fetal malformation or chromosomal abnormality; 3. Patients with liver and kidney dysfunction or heart disease; 4. Subjects who have suffered from bleeding diseases such as gastric ulcer; 5. Mental patients; 6. Alcoholics or drug addicts; 7. Subjects who do not plan to have regular prenatal examination and delivery in the research unit.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of preeclampsia; | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence of preeclampsia that appear before 34 weeks of pregnancy;incidence of pregnancy hypertention;incidence of preterm birth;incidence of severe preeclampsia; | — |
Countries
China
Contacts
Public ContactLai Baoling
Shenzhen Luohu Hospital (The Third Affiliated Hospital of Shenzhen University)
Outcome results
None listed