Parkinson's disease
Conditions
Interventions
Sponsors
Shanghai Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Those who meet the diagnostic criteria of Parkinson's disease and those with liver and kidney deficiency and Qi and blood deficiency in TCM syndrome diagnosis criteria (please refer to the plan for details); (2) The age was 50-80 years old; (3) Hoehn & Yahr grade was I-II; (4) Informed consent and willing to participate in the study.
Exclusion criteria
Exclusion criteria: (1) There was a history of repeated brain injury and stroke, accompanied by progressive progression of Parkinson's disease; (2) When symptoms appeared, antipsychotics and / or dopamine depletion drugs were used; (3) CT scan showed intracranial tumor or communicating hydrocephalus; (4) More than one relative was ill; (5) Patients with persistent remission or rapid development; (6) High dose levodopa is ineffective (7) Patients with other nervous system diseases and uncontrolled other system diseases; (8) Combined with liver, kidney, hematopoietic system and endocrine system and other serious primary diseases, mental disease and dementia patients; (9) Drug abuse and other research drugs at the same time; (10) The patient is in critical condition, and it is difficult to correctly evaluate the efficacy and safety of the trial drug; (11) Other drugs affecting this study are being used.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Faeces;UPDRS; | — |
Secondary
| Measure | Time frame |
|---|---|
| CSS;Metabolites of fecal flora;Score of TCM Syndrome Scale; | — |
Countries
China
Contacts
Public ContactNingjing Huang
Shanghai Hospital of Traditional Chinese Medicine
Outcome results
None listed