Biomarkers research for diagnosis of damp-heat syndrome of chronic liver disease

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ITMCTR

Registry ID

ITMCTR2000004010

Enrollment

Unknown

Registered

2020-08-27

Start date

2020-09-20

Completion date

Unknown

Last updated

2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic hepatitis

Interventions

None listed

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Meet the criteria for diagnosis of chronic hepatitis B or non-alcoholic fatty liver disease and TCM syndrome diagnosis; Aged 18-65 years; Sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with other liver diseases such as other hepatotropic virus infection, alcoholic fatty liver, autoimmune diseases, chronic hepatitis B and non-alcoholic fatty liver disease; 2. Patients with chronic severe hepatitis and liver cirrhosis; 3. Accompanied by severe primary disease of heart, kidney, lung, endocrine, blood, metabolism and gastrointestinal tract; 4. Mentally ill; 5. Pregnant or breastfeeding women; 6. Those who have performed gastrointestinal bariatric surgery within the past year or those who have taken weight-loss drugs; within the past 3 months have lost > 10% of their weight.

Design outcomes

Primary

Measure	Time frame
Metabolomics;Peripheral blood transcriptomics;	—

Secondary

Measure	Time frame
Blood lipids, fasting blood glucose, AFP, HBV-DNA, hepatitis B markers, HbA1c, fasting insulin;TCM Syndrome Scale;MRI-PDFF;	—

Countries

China

Contacts

Public ContactYiyang Hu

Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine

yyhuliver@163.com+86 021-20256526

Outcome results