decline in ovarian reserve, DOR
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) The age ranged from 18 to 40 years (inclusive); (2) Rare or frequent menstruation or menopause for at least 4 months; (3) Serum FSH level at least twice: 10 U / L 4 weeks); (4) AFC < 5 or serum AMH level: 0.5ng/ml < AMH < 1.1ng/ml.
Exclusion criteria
Exclusion criteria: (1) Patients are undergoing radiotherapy and chemotherapy due to malignant tumor; (2) Patients with Bilateral ovaries or uterus were removed due to gynecological surgery; (3) Patients with Ovarian hypersensitivity syndrome and other endogenous FSH increasing patients; (4) Patients with genital malformation; (5) Patients with Severe cardiovascular and cerebrovascular diseases or liver and kidney dysfunction; (6) Patients with mental disorders; (7) Those who have used hormone drugs and other immune preparations in the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TCM Syndrome Scale;Antimullerian hormone;Serum sex hormones;Uterus and ovarian ultrasound; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood routine;sas; | — |
Countries
China
Contacts
Longhua Hospital, Shanghai University of Traditional Chinese Medicine