Hashimoto's thyroiditis
Conditions
Interventions
control group:placebo
Sponsors
Wangjing Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Comply with the diagnostic criteria of Hashimoto's thyroiditis with hypothyroidism(including subclinical hypothyroidism), TCM syndrome differentiation is liver spleen deficiency, phlegm and blood stasis type; 2. Adult patients aged 18 to 65 years; 3. Signing informed consent.
Exclusion criteria
Exclusion criteria: 1. A history of malignant tumors of the thyroid gland; 2. Patients with severe heart, liver, kidney, blood system diseases or severe mental illness; 3. Pregnant or lactating women; 4. Those who are allergic to drugs; 5. Patients with hyperthyroidism.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Foxp3, ROR?t;TG-Ab, TPO-Ab;Depression and anxiety assessment;Thyroid volume and isthmus thickness;QOL;Treg/Th17;TCM symptoms and physical signs;TT3, TT4, FT3, FT4, TSH;TGF-ß, IFN-?, IL-2, IL-6, IL-10, IL-17, IL-23; | — |
Secondary
| Measure | Time frame |
|---|---|
| body weight;memory;fasting plasma glucose;blood lipoid;glycosylated hemoglobin; | — |
Countries
China
Contacts
Public ContactShiwei Liu
Wangjing Hospital, China Academy of Chinese Medical Sciences
Outcome results
None listed