Major depression disorder
Conditions
Interventions
Sponsors
Guangdong Hospital of Traditional Chinese Medicine (the Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Second Clinical School of Guangzhou University of Chinese
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18-65 years old; 2. The patients who meet the diagnostic criteria of Western medicine "depression" meet the diagnostic criteria of "depression" and "liver depression and qi stagnation syndrome"; 3. Patients with HAMD-17 score >= 17; 4. Patients who did not take antidepressant drugs at the first time; 5. Right handed subjects (according to Edinburgh Handedness scales); 6. The subjects who signed the informed consent form voluntarily participated in the study.
Exclusion criteria
Exclusion criteria: 1. Patients who have taken any antidepressants or other antipsychotics in the past have received modified electroconvulsive therapy (ECT); 2. Patients with obvious suicidal tendency assessed by specialists; 3. Patients with serious medical diseases; 4. Patients with previous history of head trauma; 5. Patients with cognitive impairment (MMSE score < 17), schizophrenia, anxiety disorder, substance abuse or other mental disorders; 6. Patients with metal implants, such as cardiac pacemaker, deep brain stimulator, vagus nerve stimulator, vascular stent, etc; 7. Patients who are willing to be pregnant or are in pregnancy or lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Event-related potential (ERP);HAMD; | — |
Secondary
| Measure | Time frame |
|---|---|
| SF-36; | — |
Countries
China
Contacts
Public ContactLing Chen
Guangdong Hospital of Traditional Chinese medicine (the Second Affiliated Hospital of Guangzhou University of traditional Chinese Medicine, the Second Clinical School of Guangzhou University of Chines
Outcome results
None listed