influenza
Conditions
Interventions
Sponsors
Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. The life contact (including dining, sleeping together, talking, traveling, etc.) with a confirmed influenza patient before enrollment is >=48 hours but not more than 1 week; 2. The time window from fever to diagnosis of the influenza patient contacted by the subject =18 years old.
Exclusion criteria
Exclusion criteria: 1) Clinically confirmed patients with influenza during the study period; 2) Subjects with flu-like symptoms at the time of enrollment; 3) Subjects who cannot maintain life contact with a confirmed influenza patient within 14 days; 4) Subjects who need to use antipyretic, analgesic, anti-inflammatory drugs, corticosteroids or immunosuppressive agents for any underlying disease; 5) Immunocompromised subjects (including subjects receiving systemic immunosuppressants or subjects infected with human immunodeficiency virus [HIV]); 6) Have received baloxavir (Xofluza), peramivir (Rapiacta), lanemivir (Inavir), oseltamivir (Tamiflu), Subjects treated with zanamivir (RELEZA) or amantadine (Symmetrel); 7) Subjects with known history of allergy to traditional Chinese medicine; 8) Subjects who have taken a Chinese medicine compound with similar effects within 30 days before screening; 9) Women who are pregnant or breastfeeding; 10) Subjects whose investigators consider any conditions or circumstances that would endanger the safety of the subjects or affect the quality of research data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of patients diagnosed with influenza within 14 days; | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of patients with symptoms of acute respiratory infection within 14 days;Proportion of patients with symptomatic influenza infection within 14 days;Time of onset of flu-like symptoms within 14 days;Proportion of patients with asymptomatic influenza infection within 14 days; | — |
Countries
China
Contacts
Public ContactLU ZHEN HUI
Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed