Chronic Atrophic Gastritis
Conditions
Sponsors
Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Aged 18-70 years, male or female; (2) Those who meet the diagnostic criteria of chronic atrophic gastritis and the test for Helicobacter pylori is negative. (13C or 14C urea breath test is required); (3) The pathological stage is OLGA-II/III. Two experts from the Department of Pathology are required for diagnosis (Pathological film reading), whose pathological conclusion should reach an agreement; (4) Voluntarily participating in this clinical trial and signing informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients with peptic ulcer, severe dysplasia of the gastric mucosa or pathological diagnosis suspected of malignant transformation; (2) Those who have severe digestive system diseases or used to have abdominal surgery; (3) Pregnant or lactating women; (4) In patients with severe heart and lung diseases , malignant tumor, severe DM and chronic liver and kidney dysfunction, ALT and AST of liver function damage were more than 1.5 times of the upper limit of normal, and renal function damage (BUN > 1.2 times of the upper limit of normal, Cr > the upper limit of normal); (5) PLT < 1.5 times of the lower limit of normal; (6) Disabled patients (blind, deaf, dumb, mental disorder, mental disorder, physical disability) as prescribed by law; (7) Alcoholics; (8) Those who are known to be allergic to two or more types of drugs or the ingredients of the drug and have allergic constitution; (9) Patients who participated in other clinical trials within 4 weeks. Patients who have taken Wifuchun, Moluodan and folic acid in within 2 weeks; (10) In the opinion of the investigator, those who will cause loss to follow-up, or not suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gastroscopy and Gastric mucosal biopcy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Indigestion symptom checklist;12-item short-form health survey, SF-12; | — |
Countries
China
Contacts
Public ContactLing jianghong
Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed