Acute pancreatitis
Conditions
Interventions
control group:placebo
Sponsors
Shanghai General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients meeting the diagnostic criteria of acute pancreatitis: according to the 2012 Atlanta classification and definition revision international consensus, the diagnosis of acute pancreatitis needs 2 of the following three characteristics: (1) Abdominal pain is consistent with the characteristics of acute pancreatitis (persistent and severe upper abdominal pain often radiates to the back); (2) The activity of serum lipase (or amylase) was at least 3 times higher than the normal upper limit; (3) Enhanced CT or infrequent magnetic resonance imaging (MRI) or abdominal ultrasonography revealed characteristic changes in acute pancreatitis. 2. Patients admitted within 72 hours after onset 3. The age of the patients is 18-75 years old 4. The patients whose family members (guardians) agreed to participate in the study, and signed informed consent and agreed to participate in the study.
Exclusion criteria
Exclusion criteria: 1. Patients with severe hypertension (systolic blood pressure greater than 180mmhg, or the average systolic blood pressure increased by more than 40mmhg) were not well controlled under the condition of drug treatment; 2. Patients with severe respiratory, cardiovascular, digestive and hematological diseases, as well as psychiatric and infectious diseases; 3. Patients with serious illness who need non medical treatment such as surgery and peritoneal lavage; 4. Patients with advanced tumor; 5. Patients with chronic renal failure caused by organic kidney disease; 6. Patients who were enrolled in other clinical trials 3 months before onset of disease; 7. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CRP;;SIRS;Local complications;Pass score;APACHE II;hospital stay;TNF-a;ICU occupancy rate;systemic complications;IL-6; | — |
Countries
China
Contacts
Public ContactXingpeng Wang
Shanghai First People's Hospital
Outcome results
None listed