Asthma-COPD Overlap, ACO
Conditions
Interventions
Sponsors
Gansu Provincial Hospital of TCM
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Asthma group: Patients with stable asthma according to gina2017 diagnostic criteria were included; 1. The symptoms such as wheezing, shortness of breath, chest tightness, cough and other symptoms recur clearly, which are related to exposure to cold air, physical and chemical stimulation, upper respiratory tract infection and exercise. The intensity changes with time, and can be relieved by antiasthmatic drugs or by itself. 2. Definite reversibility of airflow restriction: positive bronchodilation test (fevl. 0 improved more than 200 ml and more than 12%) after inhalation of bronchodilator drugs; 3. Asthma patients with fixed airflow limitation were also included in the asthma group (FEV1.0 / FVC 0.7 and greater than 92% of the predicted value; FEV1.0 and FVC were greater than 80% of the predicted value, and the shape of flow volume curve was normal; 4. Chest CT examination showed no structural lesions, no pulmonary nodules or masses larger than LCM.
Exclusion criteria
Exclusion criteria: 1. Patients with acute exacerbation within 6 weeks; 2. Chest CT showed that the diameter of lung mass was larger than 3cm; 3. Patients with other severe respiratory diseases, such as extensive bronchiectasis, interstitial lung disease, lung cancer, infectious lung disease, massive pleural effusion, etc; 4. Patients with history of chest trauma or surgery; 5. Patients with other serious diseases: heart failure, severe liver and kidney dysfunction, severe anemia, mental disorders, etc. 6. Patients who cannot cooperate with history collection, pulmonary function or chest CT examination.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Pulmonary function test; | — |
Primary
| Measure | Time frame |
|---|---|
| (Emphysema Index(EI); | — |
Countries
China
Contacts
Public ContactMa Jianke
Gansu Provincial Hospital of TCM
Outcome results
None listed