Skip to content

Study on the characteristics of immune cell infiltration and its correlation with prognosis in patients with stage III B - IV lung adenocarcinoma by PET-CT based on the theory of 'protecting field' of traditional Chinese Medicine

Study on the characteristics of immune cell infiltration and its correlation with prognosis in patients with stage III B - IV lung adenocarcinoma by PET-CT based on the theory of 'protecting field' of traditional Chinese Medicine

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2000003886
Enrollment
Unknown
Registered
2020-09-02
Start date
2020-10-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

Sponsors

Dongfang Hospital of Beijing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients with lung adenocarcinoma confirmed by histopathology and / or cytology; 2. Patients who were classified as stage III B - IV according to the 7th edition of TNM staging system published by IASLC; 3. According to the NCCN guidelines for non-small cell lung cancer (NSCLC), the first-line treatment was carried out according to the recist1.1 evaluation standard for solid tumors; 4. Patients with at least one cold ablation lesion; 5. EGFR mutation (-), ALK rearrangement (-); 6. The patients who refused chemotherapy and radiotherapy in recent 1 month planned to receive systemic therapy (oral Chinese Medicine) + local treatment (target lesion biopsy + cold ablation); 7. ECOG PS <= 2 8. Patients whose expected survival time was more than 3 months; 9. Patients with TCM syndrome conforming to any of the five syndromes of lung cancer; 10. Patients who voluntarily participated in the study and signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with multiple primary tumors; 2. Patients with other conditions not suitable for biopsy and cold ablation; 3. Patients with cold ablation lesions who have received other local minimally invasive treatment, such as radiotherapy, radiofrequency, seed implantation, etc.

Design outcomes

Primary

MeasureTime frame
lifetime;

Secondary

MeasureTime frame
Tumour Markers;Peripheral immune cell;target focus;TCM syndrome;Positive rate of immune cells;Quality of Life evaluation;

Countries

China

Contacts

Public ContactZhou Qin

Oriental Hospital of Beijing University of traditional Chinese Medicine

qinzi0424@126.com+86 15210854478

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026