Lung cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with lung adenocarcinoma confirmed by histopathology and / or cytology; 2. Patients who were classified as stage III B - IV according to the 7th edition of TNM staging system published by IASLC; 3. According to the NCCN guidelines for non-small cell lung cancer (NSCLC), the first-line treatment was carried out according to the recist1.1 evaluation standard for solid tumors; 4. Patients with at least one cold ablation lesion; 5. EGFR mutation (-), ALK rearrangement (-); 6. The patients who refused chemotherapy and radiotherapy in recent 1 month planned to receive systemic therapy (oral Chinese Medicine) + local treatment (target lesion biopsy + cold ablation); 7. ECOG PS <= 2 8. Patients whose expected survival time was more than 3 months; 9. Patients with TCM syndrome conforming to any of the five syndromes of lung cancer; 10. Patients who voluntarily participated in the study and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with multiple primary tumors; 2. Patients with other conditions not suitable for biopsy and cold ablation; 3. Patients with cold ablation lesions who have received other local minimally invasive treatment, such as radiotherapy, radiofrequency, seed implantation, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| lifetime; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tumour Markers;Peripheral immune cell;target focus;TCM syndrome;Positive rate of immune cells;Quality of Life evaluation; | — |
Countries
China
Contacts
Oriental Hospital of Beijing University of traditional Chinese Medicine