obstructive sleep apnea syndrome
Conditions
Interventions
Sponsors
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
20 Years to 55 Years
Inclusion criteria
Inclusion criteria: OSAS patients: 1. Slight to moderate patients who meet the OSAS diagnostic criteria (sleep apnea-hypopnea index 5 to 30); 2. Aged 20 to 55 years old; 3. Epworth Sleepiness Scale (ESS) > 10; 4. No abnormal brain structure and contraindications to magnetic resonance examination; 5. Those who agree and sign the informed consent; Healthy subjects: 30 healthy subjects with matching age and education level; 1. Aged 30-65 years old; 2. Does not meet the OSAS diagnostic criteria, no sleep snoring; 3. Baker Depression Scale score <3 points, Epworth Sleepiness Scale (ESS) < 10; 4. No previous history of psychiatric or other major diseases of the system.
Exclusion criteria
Exclusion criteria: 1. Body mass index (BMI) > 30; 2. Other diseases that cause similar symptoms: simple snoring, severe anatomical problems at upper airway, central apnea and Chen Shi's breathing, and other diseases (such as narcolepsy, lack of sleep, periodic limb movement disorders, Ning leg syndrome, abnormal thyroid function, third-degree enlarged tonsils, use of alcohol or drugs); 3. Combined with cardiovascular, liver, kidney, hematopoietic system diseases, serious primary diseases, cancer nose Tumor and oral cancer; 4. Eliminate permanent mental illness: lifelong bipolar disorder, any type of mental illness Schizophrenia, any type of delusion disorder, any type of dementia, organic brain disorders, and abuse of alcohol or other substances in the 2 years before the onset of labor illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Epworth scale will be used to evaluate subjects' subjective sleepiness; | — |
Secondary
| Measure | Time frame |
|---|---|
| Use Self-rating Depressiong Scale (SDS) and Self-rating Anxiety Scale (SAS) to evaluate the emotional state of subjects;Adverse reactions of acupuncture.;The Pittsburgh sleep quality index (PSQI) will be used to evaluate changes in subjects' actual sleep time, sleep efficiency, sleep latency and other indicators;Using magnetic resonance to observe changes in brain function and structure before and after treatment;Auditory semantic test is used to evaluate episodic memory, number breadth test is used to evaluate language processing ability, connection A and B test is used to evaluate executive function, digital symbol test is used to evaluate patient information;Polysomnography (PSG) records the number of recurrent episodes of apnea and hypopnea during night; | — |
Countries
China
Contacts
Public ContactQi Xiaohuan
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
Outcome results
None listed