ST segment elevation myocardial infarction
Conditions
Sponsors
Shuguang Hospital of Shanghai University of Traditional Chinese
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) patient aged 18 and 85 years old; (2) It conforms to the diagnosis of acute myocardial infarction in Western medicine, and is diagnosed as "death heartache" by Traditional Chinese medicine. The syndrome belongs to the syndrome of "blood stasis and obstruction"; (3) Patients with single-vessel, double-vessel or three-vessel coronary lesions diagnosed by emergency coronary angiography and and PCI with onset time less than 6 hours.
Exclusion criteria
Exclusion criteria: 1. Patients who did not undergo coronary angiography +PCI; 2. Pregnant women and lactating women; 3. Chest pain caused by other heart diseases, severe cardiac neurosis, menopausal syndromes, hyperthyroidism, cervical spondylosis, biliary disease, stomach and esophageal reflux, etc.; 4. Patients with severe heart and lung dysfunction and severe arrhythmia; 5. Patients with multiple organs such as heart, liver, brain and kidney, as well as hematopoietic system and other serious primary diseases, malignant tumors, or mental diseases; 6. Patients who are known to be allergic to such drugs and have a severe allergic constitution; 7. Recent (within 1 month) major trauma or surgical history, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| echocardiography (LVDd, LVSd, IVSd, LVpWd, LVEF, LVMI, LVRI);lymphocyte (Th1, Th2);inflammatory factor (IL-6, IL-17, IL-10, TGF-beta etc.);chemokine receptor (CXCR1-4\CCR-7 etc.);chemotactic factor (CCL1-5, 11 etc.); | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood routine examination, hypersensitive CRP, SOD, BNP, TNI.;Blood routine and stool routine;TCM symptom improvement score;Liver function (ALT, AST, TBIL, ALP, GT), renal function (BUN, Cr, urinary microalbumin), urinary routine and urinary sediment microscopic examination, creatine kinase CK;Score of TCM syndrome of Heat and Phlegm-Blood Stasis ;Adverse events and adverse reactions shall be recorded at any time; | — |
Countries
China
Contacts
Public ContactWANG Xiao-long
Shuguang Hospital of Shanghai University of Traditional Chinese
Outcome results
None listed