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A single center, randomized controlled trial on the treatment of elderly patients with acute myeloid leukemia by attack and reinforcement combined with demethylation

A single center, randomized controlled trial on the treatment of elderly patients with acute myeloid leukemia by attack and reinforcement combined with demethylation

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2000003828
Enrollment
Unknown
Registered
2020-08-28
Start date
2020-09-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

elderly patients with acute myeloid leukemia

Interventions

Sponsors

Yueyang integrated traditional Chinese and Western Medicine Hospital Affiliated to Shanghai University of traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria of Western medicine for senile AML; 2. Accord with the diagnostic criteria of TCM syndrome of senile AML; 3. Aged 60 to 80 years old; 4. The patients with an estimated survival time of more than 3 months; 5. Willing to accept the treatment of this program and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Acute promyelocytic leukemia; 2. Patients with serious organic diseases such as heart, brain, liver and kidney, and patients with other malignant tumors and mental diseases; 3. Coexisting diseases with any significant abnormalities or poor nutritional status, which affect the life safety and compliance of patients; 4. Allergy to any drug involved in the scheme; 5. Participate in other clinical researchers one month before enrollment.

Design outcomes

Primary

MeasureTime frame
overall remission rate;

Secondary

MeasureTime frame
RD level of bone marrow;Complete remission rate;Quality of life assessment;Quantitative score of TCM Syndromes;

Countries

China

Contacts

Public ContactBao Jizhang

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine

xyzsbjz@126.com+86 13301907859

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026