Sjogren syndrome
Conditions
Interventions
Sponsors
Yueyang Integrated Traditional Chinese and Western Medicine Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. SS patients who meet the above diagnostic criteria of traditional Chinese and Western medicine. 2. Patients with moderate activity (essdai score 4-6). 3. Age of subjects: 18-65 years old. 4. Patients who have not used traditional Chinese medicine in the past, or have been interrupted for more than 2 months. 5. Women of childbearing age agreed to take effective contraceptive measures during the trial. 6. Patients who voluntarily sign informed consent and comply with the requirements of the study protocol.
Exclusion criteria
Exclusion criteria: 1. Patients with severe or uncontrolled cardiovascular, liver, kidney, brain and hematopoietic system. 2. Patients with other connective tissue diseases, drug-induced lupus syndrome, tuberculosis and psychosis. 3. Pregnant or lactating women. 4. Patients with ALT or ast more than twice the upper limit of normal value, or total bilirubin greater than the upper limit of normal value. 5. Patients with allergic constitution.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tear film rupture time;ESR;Corneal fluorescent stain;Serum IgG;Schirmer's test;Saliva flow rate;Serum ß2 microglobulin;CRP;RF; | — |
Secondary
| Measure | Time frame |
|---|---|
| Drug side effects;C3;Hormone withdrawal;C4;Number of relapses, degree of progress; | — |
Countries
China
Contacts
Public ContactDan Wang
Yueyang Integrated Traditional Chinese and Western Medicine Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed