Senile Hypertension
Conditions
Interventions
Sponsors
Yueyang Hospital of Intergrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Old age is defined as age >= 60 years old. two. Meet the diagnostic criteria of essential hypertension. 3. Before the test, ambulatory blood pressure examination showed at least one of the following abnormalities: 24-hour average systolic or diastolic blood pressure was not up to standard, early morning hypertension, abnormal circadian rhythm of blood pressure, abnormal blood pressure variability. 4. Understand and agree to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with malignant hypertension. 2. Patients with severe cardiovascular and cerebrovascular diseases and respiratory diseases. 3. Patients with severe abnormality of liver and kidney function, malignant tumor and anemia. 4. Patients with mental illness and patients who are unable to describe their symptoms and have difficulties in understanding. 5. Patients who are allergic to the drugs used in this study. 6. Women during pregnancy and lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure load;TCM syndrome score;Blood pressure circadian rhythm;Mean of 24-hour blood pressure;Blood pressure variability; | — |
Secondary
| Measure | Time frame |
|---|---|
| Target organ damage index;Serum homocysteine;Detection of intestinal flora abundance in feces;Serum creatinine;Detection of inflammatory factors in peripheral blood monocytes;Serum C-reactive protein;Detection of microRNA in serum;Urinary Microalbumin / urinary creatinine ratio; | — |
Countries
China
Contacts
Public ContactZhangTeng
Yueyang Hospital of Intergrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine
Outcome results
None listed