The exploration of the treatment mode of electroacupuncture combined with SSRI drugs for different degrees of first-onset depression

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ITMCTR

Registry ID

ITMCTR2000003720

Enrollment

Unknown

Registered

2020-08-26

Start date

2020-10-31

Completion date

Unknown

Last updated

2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Interventions

Group B:Sham EA and Escitalopram

Group A:Electroacupuncture and Escitalopram

Group D:Sham EA and Escitalopram

Group C:Electroacupuncture and placebo drugs

Group E:Sham EA and placebo drugs

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for depression in the 5th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5); 2. Patients who have not taken any antidepressants in the past; 3. Assessed as low suicide risk; 4. 18 to 60 years old; 5. HDRS-17 >= 18 points; 6. Have never received acupuncture treatment; 7. Sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Bipolar disorder, or depression syndrome in other disease states; 2. Schizophrenia and other psychotic disorders secondary to depression; 3. Those who have evidence of alcohol or other substance dependence or abuse; 4. Organic brain diseases and other serious physical diseases; 5. Pregnant and lactating women.

Design outcomes

Primary

Measure	Time frame
HDRS-17;	—

Secondary

Measure	Time frame
TESS;SF-36;PHQ-9;clinical cure rate;Clinical remission rate;	—

Countries

China

Contacts

Public ContactXu Shifen

Shanghai Municipal Hospital of Traditional Chinese Medicine

xu_teacher2006@126.com+86 13761931393

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026