Gastric Cancer
Conditions
Interventions
Sponsors
Shuguang Hospital, Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with gastric cancer who met the diagnostic criteria and had positive HER-2 test and TNM stage IV; 2. First-line palliative chemotherapy is proposed; 3. At least one measurable lesion displayed by imaging examination (PET-CT, CT, MRI, bone scan, gastroscopy); 4. The estimated survival time is greater than or equal to 6 months; 5. TCM syndromes belong to the miscellaneous syndromes of cold and heat; 6. Age between 18 and 75 years old (including 18 and 75 years old); 7. Physical status score ECOG PS score 0-1; 8. Blood routine, heart, liver and kidney function, cardiac ultrasonography, coagulation function, electrocardiogram and other indicators are in line with the treatment indications. 9. Voluntarily accept the observation of this research plan, with good compliance, clear thinking, clear expression and normal language and sensory response. 10. Subjects were able to understand the study and sign informed consent and were willing to follow up.
Exclusion criteria
Exclusion criteria: 1. Severe diseases such as heart, liver, kidney and hematopoietic system, pregnancy or lactationand uncontrollable psychosis. 2. Symptomatic brain metastases, with complications associated with brain metastasis and cognitive impairment. 3. Patients with dysphagia, complete or incomplete gastrointestinal obstruction, active gastrointestinal bleeding, perforation and other contraindications to the use of chemotherapeutic drugs. 4. Allergies to this drug are known. 5. Active tuberculosis and other serious infectious diseases. 6. Taking part in or taking part in clinical trials of other drugs within 4 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression free survival;Safety; | — |
Secondary
| Measure | Time frame |
|---|---|
| DCR;TCM syndromes points;ORR;Quality of life;Tumor marke;Immune function; | — |
Countries
China
Contacts
Public ContactLiu Ningning
Department of Medical Oncology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine
Outcome results
None listed