Infertility Due to Decreased Ovarian Reserve
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Women aged from 22 to 40 with normal development; (2) In line with the Western diagnostic criteria and irregular menstruation syndrome of kidney deficiency syndrome; (3) The patient voluntarily accepts the experiment and can persist in treatment.
Exclusion criteria
Exclusion criteria: (1) Congenital uterine malformations; (2) There are uncured endometrial diseases; (3) Bilateral hydrosalpinx; (4) Combined with serious medical and surgical diseases, including diabetes, hypertension, thyroid disease, etc.; (5) Patients who are unable to correctly understand and answer the questionnaire, such as patients with severe mental illness, patients with hearing, speaking, reading and writing disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pregnancy rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| reactive oxygen species, ROS;FSH;E2;phosphatidylinositol-3-kinase, PI3K;AMH;proteinkinase B, AKT;nuclear factor erythroid 2-related factor 2, Nrf2;receptor for advanced glycation end products, RAGE;advanced glycation end products, AGEs;Superoxide dismutase, SOD;Number of antral follicles;high mobility group protein box 1, HMGB1; | — |
Countries
China
Contacts
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine