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The therapeutic effect of Zhu's Tiaojing Cuyun Recipe on infertility due to decreased ovarian reserve: a prospective, randomized, double-blind, controlled clinical research

The therapeutic effect of Zhu's Tiaojing Cuyun Recipe on infertility due to decreased ovarian reserve: a prospective, randomized, double-blind, controlled clinical research

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2000003691
Enrollment
Unknown
Registered
2020-08-25
Start date
2020-10-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility Due to Decreased Ovarian Reserve

Interventions

Sponsors

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
22 Years to 40 Years

Inclusion criteria

Inclusion criteria: (1) Women aged from 22 to 40 with normal development; (2) In line with the Western diagnostic criteria and irregular menstruation syndrome of kidney deficiency syndrome; (3) The patient voluntarily accepts the experiment and can persist in treatment.

Exclusion criteria

Exclusion criteria: (1) Congenital uterine malformations; (2) There are uncured endometrial diseases; (3) Bilateral hydrosalpinx; (4) Combined with serious medical and surgical diseases, including diabetes, hypertension, thyroid disease, etc.; (5) Patients who are unable to correctly understand and answer the questionnaire, such as patients with severe mental illness, patients with hearing, speaking, reading and writing disorders.

Design outcomes

Primary

MeasureTime frame
Pregnancy rate;

Secondary

MeasureTime frame
reactive oxygen species, ROS;FSH;E2;phosphatidylinositol-3-kinase, PI3K;AMH;proteinkinase B, AKT;nuclear factor erythroid 2-related factor 2, Nrf2;receptor for advanced glycation end products, RAGE;advanced glycation end products, AGEs;Superoxide dismutase, SOD;Number of antral follicles;high mobility group protein box 1, HMGB1;

Countries

China

Contacts

Public ContactLi Dong

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine

yydongli@163.com+86 18930565213

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026