Knee osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients who meet the OA diagnostic criteria; 2. Patients with aged >=50 and <=70 years old; 3. Agree to operate on the same operator (operated by a doctor with senior professional title, adopting unified standardized OWHTO technology, 3D printing osteotomy guide plate and internal fixation materials of the same manufacturer); 4. Patients who are able to cooperate with specific treatment: those who have specified time for reexamination and regular rehabilitation exercise, and complete data.
Exclusion criteria
Exclusion criteria: 1. People with allergies and allergic to oral Chinese patent medicines; 2. Suffering from endocrine diseases such as diabetes, hyperthyroidism, and hyperparathyroidism; 3. Liver and kidney insufficiency, and have used hormones or other drugs that affect bone metabolism within six months; 4. Suffering from rheumatoid arthritis, bone tumor or Paget disease; 5. It is difficult to determine the effect of medication without following the doctor's order
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| X-ray; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ca2+;KSS score;ß-CTX;PINP;Visual Analogue Scale/Score;ALP;CT;BMP; | — |
Countries
China
Contacts
Xuanwu Hospital Capital Medical University