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Effects of Bushen Huoxue method in fracture healing after biplanar open wedge high tibial osteotomy

Effects of Bushen Huoxue method in fracture healing after biplanar open wedge high tibial osteotomy

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2000003676
Enrollment
Unknown
Registered
2020-08-24
Start date
2018-01-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis

Interventions

Sponsors

Xuanwu Hospital Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients who meet the OA diagnostic criteria; 2. Patients with aged >=50 and <=70 years old; 3. Agree to operate on the same operator (operated by a doctor with senior professional title, adopting unified standardized OWHTO technology, 3D printing osteotomy guide plate and internal fixation materials of the same manufacturer); 4. Patients who are able to cooperate with specific treatment: those who have specified time for reexamination and regular rehabilitation exercise, and complete data.

Exclusion criteria

Exclusion criteria: 1. People with allergies and allergic to oral Chinese patent medicines; 2. Suffering from endocrine diseases such as diabetes, hyperthyroidism, and hyperparathyroidism; 3. Liver and kidney insufficiency, and have used hormones or other drugs that affect bone metabolism within six months; 4. Suffering from rheumatoid arthritis, bone tumor or Paget disease; 5. It is difficult to determine the effect of medication without following the doctor's order

Design outcomes

Primary

MeasureTime frame
X-ray;

Secondary

MeasureTime frame
Ca2+;KSS score;ß-CTX;PINP;Visual Analogue Scale/Score;ALP;CT;BMP;

Countries

China

Contacts

Public ContactGuanglei Cao

Xuanwu Hospital Capital Medical University

gregary111@163.com+86 13910785151

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026