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Multi center clinical study of Shenfu Xiangshao Decoction in the treatment of coronary heart disease complicated with heart failure

Multi center clinical study of Shenfu Xiangshao Decoction in the treatment of coronary heart disease complicated with heart failure

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2000003670
Enrollment
Unknown
Registered
2020-08-24
Start date
2020-10-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

heart failure

Interventions

Sponsors

Shanghai Putuo District Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1) They are over 18 years old and have no gender limit; 2) Left ventricular ejection fraction (LVEF) was less than 50% (echo); 3) Patients with chronic heart failure and NYHA class II or above have symptoms of chest tightness / shortness of breath / fatigue / hyperhidrosis; 4) Definite diagnosis of coronary heart disease (including history, clinical symptoms, signs, imaging examination); 5) Understand and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1) NYHA class I patients had no clinical symptoms; 2) Patients who planned to undergo revascularization in recent 2 months; 3) Patients preparing for heart transplantation or CRT; 4) Patients with acute pulmonary edema or acute hemodynamic disorder; 5) Patients with strict liquid intake limit not exceeding 500ml / day; 6) Women who have or plan to become pregnant; 7) Those who have participated in any drug clinical trials within the first 3 months; 8) The survival time was less than 2 months; 9) According to the investigator's judgment, the patient could not complete the study or could not comply with the requirements of this study.

Design outcomes

Primary

MeasureTime frame
6-minute walking distance;Ejection fraction;

Secondary

MeasureTime frame
Quality of life score;NT-proBNP;All cause mortality;TCM syndrome score;Readmission for worsening heart failure;

Countries

China

Contacts

Public ContactDaying Wang

Shanghai Putuo District Central Hospital

daying_wang@aliyun.com+86 13818588169

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026