Knee Osteoarthritis
Conditions
Interventions
Experimental Comparator treatment:meridian electroacupunctureAcupuncture treatment will be the Traditional Chinese Medicine type(Liangqiu acupoint,Futu acupoint,Xiyan acupoint,Dubi acupoint). Acupunct
Active Comparator:Acupuncture treatment will be the Traditional Chinese Medicine type(Xuehai acupoint,Liangqiu acupoint,Ququan acupoint, Xiyangguan acupoint,Zusanli acupoint,Yinlingquan acupoint,Sanyi
control group:False Needle treatment will be modeled the Traditional Chinese Medicine type. (Xuehai acupoint,Liangqiu acupoint,Ququan acupoint, Xiyangguan acupoint,Zusanli acupoint,Yinlingquan acupoin
Sponsors
Shanghai Longhua Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients who meet the western medicine diagnostic criteria of knee osteoarthritis; 2. Aged between 50 and 75 years; 3. Patients in line the level of radiological classification for knee osteoarthritis degeneration; 4. Patients who did not use glucocorticoid via oral administration or intramuscular, articular, or soft tissue injection four weeks before accepting the test agent; 5. Patients who signed the informed consent and ensured the compliance.
Exclusion criteria
Exclusion criteria: 1. Patients with long-term oral administration of agents for knee osteoarthritis, and still in the drug effect period, without elution; 2. Patients with severe heart, brain, liver, kidney or lung dysfunction; 3. Patients with other knee diseases found in arthroscopic surgery; 4. Patients who have accepted other relevant treatments, which may affect the observation on the effects of this study; 5. Patients with mental illness; 6. Patients with coagulation dysfunction; 7. Patients with articular surgical treatment; 8. Patients with an indication for joint surgery 9. Patients with a history of abuse of opioid analgesics, sedative hypnotics or alcohol; 10. Patients with poor compliance, who were unable to meet the requirements for follow-up. 11. Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lequesne index;VAS score;Six-minute walking test;WOMAC;The Medical Outcomes Study short form health survey-36; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ultrasound of the knee joint;3D Gait Analysis;Proteome resequencing: peripheral blood.;Isometric muscle strength test;Knee CT;NIR-ICG near-infrared detection;inguinal lymph node ultrasound; | — |
Countries
China
Contacts
Public ContactWang Yongjun
Shanghai Longhua Hospital
Outcome results
None listed