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Clinical study of heyingshui decoction in optimizing anti VEGF treatment of macular edema due to retinal vein occlusion

Clinical study of heyingshui decoction in optimizing anti VEGF treatment of macular edema due to retinal vein occlusion

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2000003614
Enrollment
Unknown
Registered
2020-08-21
Start date
2020-10-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

macular edema due to retinal vein occlusion

Interventions

3:Oral traditional Chinese medicine decoction combined with anti VEGF injection on demand
1:In the first 6 months, the patients were injected once a month, and then followed up every month to re inject according to the needs of the disease
2:The first injection, followed by a monthly follow-up, according to the needs of the disease re injection
36+prn1+prn

Sponsors

Longhua Hospital Affiliated to Shanghai University of traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) The macular fovea thickness was more than or equal to 300um. (2) It is in accordance with the diagnostic criteria of TCM syndrome of blood stasis obstructing collaterals and water dampness stopping inside. (3) They are between 25 and 80 years old. (4) In our hospital, no other traditional Chinese medicine, macular grid photocoagulation, intravitreal drug injection or vitrectomy were taken.

Exclusion criteria

Exclusion criteria: (1) Patients who had received oral other drugs, macular grid photocoagulation, intravitreal drug injection or vitrectomy within 3 months before treatment. (2) Patients with chronic fundus diseases. For example, glaucoma, optic atrophy, macular degeneration, diabetic retinopathy, moderate cataract and other eye diseases that seriously affect vision; (3) The refractive stroma is not clear, which affects the fundus observer. (4) Patients with severe systemic diseases. (5) Those who have taken other traditional Chinese medicine or drugs for promoting blood circulation and promoting diuresis within 14 days. (6) Mental disorders are difficult to cooperate with treatment. (7) The general condition is not suitable for the patients treated in this study protocol.

Design outcomes

Secondary

MeasureTime frame
effect of TCM Syndrome;Determination of fundus hemorrhage and exudation;Blood flow density of retinal capillary plexus, Area of FAZ;Hemodynamic indexes of CRA, CRV;

Primary

MeasureTime frame
BCVA;fovea thickness;

Countries

China

Contacts

Public ContactSu Jing

Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine

sujinglucky@163.com+86 13917658399

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026