Restless leg syndrome
Conditions
Sponsors
Yueyang Integrative Medicine Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) All primary RLS patients meet the 2014 international RLS research group diagnostic criteria; (2) No serious heart and lung diseases, no obvious liver and kidney damage, serum ferritin & GT; 50 mg/L, male hemoglobin >=120 g/L, female hemoglobin >= 110 g/L; (3) All subjects did not take drugs (such as tricyclic antidepressants, sleeping pills, and dopamine drugs, etc.) that affect the change of sleep and periodic limb movement index within 2 weeks before the examination.; (4) Sleep Apnea hypopnea index (Apnea/ Hypopnea index (AHI)) of all subjects required & LT<10/h; (5) Physical examination of the nervous system is normal.
Exclusion criteria
Exclusion criteria: (1) Serum ferritin <= 50 mg/L, male hemoglobin & LT < 120 g/L, female hemoglobin & LT < 110 g/L patients or patients with arthritis, Parkinson's disease, peripheral neuropathy and nerve root disease; (2) Persons with serious heart and lung diseases and obvious liver and kidney damage; (3) Take drugs (such as tricyclic antidepressants, sleeping pills, and dopamine drugs) that affect the change of sleep and periodic limb movement index within 2 weeks before polysomnography examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chalder Fatigue Scale;Polysomnogram;Depression scale;PSQI scale;The brain PET-CT;The brain fMRI;Anxiety Scale;Self-rating scale for the severity of restless leg syndrome;RLS Quality of Life Scale; | — |
Countries
China
Contacts
Public ContactWenjia Yang
Yueyang Integrative Medicine Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed