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The effect of joint acupuncture and traditional Chinese medicine pretreatment on the high qualified embryo rate of elderly renal deficiency DOR women undergoing IVF/ ICSI- ET and the regulation on the cervicovaginal microbiome and local immune response: a prospective open-label randomized controlled trial

The effect of joint acupuncture and traditional Chinese medicine pretreatment on the high qualified embryo rate of elderly renal deficiency DOR women undergoing IVF/ ICSI- ET and the regulation on the cervicovaginal microbiome and local immune response: a prospective open-label randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2000003569
Enrollment
Unknown
Registered
2020-08-16
Start date
2020-11-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

Sponsors

Tongji Hospital Affiliated to Tongji University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
35 Years to 42 Years

Inclusion criteria

Inclusion criteria: 1. Aged between 35 and 42 years old; 2. conforms to the indications for IVF/ICSI-ET; 3. conforms to the diagnostic criteria of DOR; 4. conforms to the diagnostic criteria of renal deficiency syndrome in Chinese medicine; 5. The main causes of infertility are fallopian tube factors, and exclude hypothalamus and other endocrine diseases(hypothyroidism or hyperthyroidism, diabetes, etc.), polycystic ovary syndrome (PCOS), severe pelvic endometriosis, adenomyosis, etc.; 6. Patients agree to participate in this clinical study and sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Within 3 months, there was a history of steroid hormone treatment and a history of uterine operation; 2. It has been clear that there are obvious and serious other organic lesions in the reproductive organs; 3. With ovarian premature failure, previous ovarian surgery history and only single ovarian; 4. PCOS, adenomyosis, uterine malformations, chromosomal abnormalities, ovarian tumors, and other endocrine diseases(diabetes, thyroid dysfunction, etc.); 5. Hereditary diseases that are not suitable for production, and are currently not capable of being diagnosed by preimplantation genetics under the Maternal and Child Health Act; 6. The couple merged with Severe primary diseases of the cardiovascular, hepatic, renal or hematopoietic systems , or with mental illness; 7. Either of the couple has serious addictions such as drug use and exposure to teratogenic rays, poisons, and drugs and is in the action period; 8. Allergic constitution and allergy to many drugs; 9. Can not insist on treatment.

Design outcomes

Primary

MeasureTime frame
high qualified embryo rate;

Countries

China

Contacts

Public ContactHong Yan

Tongji Hospital Affiliated to Tongji University

have_time_off@126.com+86 13917858864

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026