Alcoholic Liver Disease
Conditions
Interventions
Sponsors
Longhua Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-70 years old; 2. The alt, AST or ? - GT were 1.5 times higher than the normal value; 3. Those who did not take relevant drugs within one week 4. Those who deny that hypertension, diabetes, cardiovascular and cerebrovascular diseases need to take all kinds of Western medicine for a long time; 5. During the study period, there was no pregnancy plan or postpartum non lactation period; 6. Normal mental and intelligence can cooperate with the researcher; 7. Informed consent and willing to accept the treatment plan.
Exclusion criteria
Exclusion criteria: 1. Other liver diseases such as hepatitis B and C were found; 2. Those who relapsed drinking during the treatment; 3. Those who participated in other clinical studies or used other treatment schemes during the observation period; 4. Use other drugs by oneself during case observation; 5. Failure to complete follow-up or withdrawal from treatment due to other reasons; 6. During the study period, patients with severe cerebrovascular disease, hematopoietic system and mental diseases; 7. Pregnant women during observation; 8. Autoimmune liver disease, diabetic endocrine fatty liver disease, drug-induced liver disease, toxic hepatitis, liver cancer, nonalcoholic fatty liver disease, hepatorenal failure, occult hepatitis, liver disease with unknown causes; 9. Allergic to polyene phosphatidylcholine and / or traditional Chinese medicine; 10. Those who can't insist on completing the treatment or main observation indexes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Procollagen III;Hyaluronic Acid;Laminin;?-glutamyl transpeptidase;Collagen IV;tumor necrosis factor alpha;alpha smooth muscle actin;Alkaline phosphatase;TCM syndrome efficacy;APRI Score;Total bilirubin;Fibrosis 4 Score;Direct bilirubin;Alanine aminotransferase;liver stiffness measurement;Aspartate aminotransferase;Albumin;Mean Corpuscular Volume; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total Cholestero;Triglycerides; | — |
Countries
China
Contacts
Public ContactXing Lianjun
Longhua Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed