Colorectal Cancer
Conditions
Interventions
Sponsors
Department of Gastrointestinal surgery,Guangdong Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) The age of the patients was 18-75 years old; (2) Radical resection of colorectal cancer (negative margin) was performed; (3) Patients with stage II high risk and stage III colorectal cancer confirmed by histology; (4) No liver, peritoneal or distant metastasis was found; (5) Patients with colorectal cancer who received standard chemotherapy or radiotherapy after operation and had no recurrence or metastasis at the end of radiotherapy and chemotherapy; (6) ECoG (Eastern Cooperative Oncology Group) score was 0-1; KPS score was 70 or above; (7) Liver function: SGOT and SGPT were less than 1.5 times of normal value, bilirubin was less than 1.5 mg / dl; (8) Renal function: creatinine < 1.8mg/dl.
Exclusion criteria
Exclusion criteria: (1) Allergic to the drug of this scheme; (2) Pregnant or lactating women with fertility requirements during the study period; (3) Severe hypertension, coronary heart disease, diabetes and so on, which are under control for half a year due to cardiovascular accident and poor drug control, are accompanied with other uncontrollable benign diseases such as lung, kidney, liver, infection, etc; (4) Participate in other studies before and during treatment; (5) There was a history of other malignant tumors or multi-source tumors within one year; (6) Chronic hepatitis B or C (high copy viral DNA) or activity in HIV infection history or active phase; (7) Patients with tuberculosis or seizures who need to be treated (e.g. steroids or antiepileptic therapy).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 3 yeah Disease-free Survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| OS;Quality of life;Median survival time; | — |
Countries
China
Contacts
Public ContactWei Wang
Guangdong Provincial Hospital of Chinese Medicine
Outcome results
None listed