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The immediate analgesia of acupuncture for biliary colic and the underlying peripheral-cerebral influence: a randomized controlled trial

Correlation Study of Gallbladder Point-Gallbladder-Central Center Based on Multi-modal Synchronous Acquisition and Fusion Analysis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2000003458
Enrollment
Unknown
Registered
2020-07-05
Start date
2020-07-15
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Biliary colic

Interventions

Sponsors

Chengdu University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: (1) Age between 18 and 60 years and right-handed. (2) Mild tenderness in the right upper abdomen, with Murphy's sign (-). (3) Not taken any NSAIDs within two weeks. (4) Signed informed consent.

Exclusion criteria

Exclusion criteria: (1) Calculus in bile duct. (2) Acute cholecystitis, acute suppurative, gangrenous, incarcerated cholecystitis and perforation of gallbladder with diffuse peritonitis, etc. (3) Serious complications or primary diseases such as cerebral, cardiovascular, liver, kidney, endocrine and hematopoietic system. (4) Severe digestive system diseases, such as peptic ulcer, upper gastrointestinal hemorrhage, gastric tumor, Crohn's disease, irritable bowel syndrome, etc. (5) Other causes of upper abdominal pain, such as gastritis, enteritis, pancreatitis, peritonitis, etc. (6) White blood cells (WBCs)>15×10^9/L with systemic inflammatory response. (7) Mental disorders such as serious anxiety and depression (the Zung Self-Rating Anxiety Scale (SAS) scores = 70 or the Zung Self-Rating Depression Scale (SDS) scores >=72); (8) Taking other medications, such as analgesic drugs. (9) Pregnancy or lactating women. (10) Participating in any other clinical trials in the past three months. (11) Received any acupuncture treatment in recent 1 month.

Design outcomes

Primary

MeasureTime frame
Numerical Rating Scale (NRS);

Secondary

MeasureTime frame
Local pain threshold at acupoints;the Chinese version of modified Massachusetts General Hospital Acupuncture Sensation Scale (C-MASS);the Zung Self-Rating Depression Scale;The 12-item Short Form Health Survey;fNIRS;the Zung Self-Rating Anxiety Scale;

Countries

China

Contacts

Public ContactRuirui Sun

Chengdu University of Traditional Chinese Medicine

sunruirui@cdutcm.edu.cn+86 13882178547

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026