Hyperplastic scar after burn
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Hypertrophic scar formed after burn and scald for more than 6 months without signs of regression; 2. The scar is raised on the surface of skin, hard and smooth; 3. It has the clinical symptoms of continuous growth, redness, pain and itching, and has no tendency of self-healing and can not subside by itself; 4. The lesions did not exceed the original damage margin, and the boundary was regular. There was no infiltration into the surrounding normal tissues and did not grow like crab feet; 5. Scar length >= 8cm, thickness >= 2mm; 6. Patients who have not received glucocorticoid injection, other laser therapy and other invasive treatment in recent one year; 7. Patients aged 18-55 years, male or female, volunteer; 8. Patients and their families agree and sign the informed consent for special treatment.
Exclusion criteria
Exclusion criteria: 1. The lesions are keloid or keloid tendency, such as exceeding the original damage edge, irregular boundary, infiltrating into surrounding normal tissues and growing like crab feet; 2. Pregnant or lactating women; 3. Patients with systemic diseases (liver and kidney insufficiency, cardiopulmonary dysfunction, hyperlipidemia, hypercholesterolemia, anemia, etc.); 4. Patients with serious skin diseases, such as psoriasis, scleroderma, etc; 5. Patients who quit the experiment before the end of treatment, such as death, loss of follow-up, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VSS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Microbiota in scar;VRS; | — |
Countries
China
Contacts
Wuxi Third People's Hospital