Parkinson's disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients who meet the diagnostic criteria of PD and 1-3 grading criteria; 2. Patients aged 45-80 years; 3. If the patient is treated with anti PD drugs, the dose is stable for at least 30 days; 4. Patients can cooperate with all examinations, tests, questionnaires, etc. required by the study (such as long-term Mrs examination); 5. Patients who voluntarily participated in the study and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. MRI was performed in patients with intracranial organic lesions; 2. Patients with limb trauma, neuromuscular junction and muscle diseases, diabetic peripheral neuropathy, rheumatism and immunity can lead to systemic diseases of peripheral neuropathy; 3. Patients with major diseases such as severe heart, liver and kidney dysfunction, mental and neurological diseases, severe infection, tumor, etc.; 4. The allergic constitution is allergic to the known related traditional Chinese medicine ingredients; 5. Patients who have ever been treated with traditional Chinese medicine or proprietary Chinese medicine for PD symptoms, and the time interval between the last medication and this visit is less than 7 days; 6. Patients who have received deep brain stimulation; 7. Patients who cannot complete the examination due to other diseases; 8. Patients who participated in other clinical trials in the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| relevant indicators of 1H-MRS examination;relevant indicators of Emg somatosensory evoked potential; | — |
Countries
China
Contacts
Fujian University of Traditional Chinese Medicine