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Effect of retention enema with Dahuang Wumei Decoction on intestinal microecological imbalance in patients with HBV-ACLF

Effect of retention enema with Dahuang Wumei Decoction on intestinal microecological imbalance in patients with HBV-ACLF

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2000003405
Enrollment
Unknown
Registered
2020-06-17
Start date
2020-06-30
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HBV-ACLF

Interventions

Sponsors

The fifth medical center of the General Hospital of the people's Liberation Army of China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Inpatients who meet the diagnostic criteria of chronic plus acute (subacute) liver failure; 2. Patients with chronic hepatitis B liver disease; 3. Patients who voluntarily participated in the study and signed informed consent; 4. Patients aged 16-65 years.

Exclusion criteria

Exclusion criteria: Subjects with any of the following conditions will not be able to participate in this study: 1. Patients with acute liver failure, subacute liver failure and chronic liver failure; 2. Chronic plus acute (subacute) liver failure caused by non HBV infected patients (including autoimmunity, drug, alcohol, poisoning, parasitism); 3. Pregnant or lactating women; 4. Patients with primary liver cancer; 5. Patients with other serious systemic diseases and psychosis; 6. Anti HIV positive; patients with hepatitis A, C, D, E virus or cytomegalovirus, EB virus infection; 7. Patients who used antibiotics, hormones, immunosuppressants, chemotherapy drugs, etc. in the past month; 8. Patients with severe hemorrhoids, anal stenosis and artificial anus; 9. Patients with poor compliance cannot guarantee to complete the study according to the study plan; 10. Patients taking probiotics and other microbial preparations.

Design outcomes

Primary

MeasureTime frame
intestinal microecological;

Countries

China

Contacts

Public ContactGong Man

The fifth medical center of the General Hospital of the people's Liberation Army of China

gongman302@163.com+86 13910123785

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026