Chronic Glomerulonephritis CKD1-2
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. 160 patients with primary chronic glomerulonephritis had typical clinical symptoms of chronic nephritis, which met the western medicine diagnostic criteria of chronic nephritis. 2. The syndrome differentiation of traditional Chinese medicine belongs to the type of "deficiency of spleen and kidney qi, and dampness heat and stasis"; 3. Patients with chronic kidney disease (CKD) stage 1-2, GFR >= 60ml / min / 1.73m2; 4. Patients aged 18-65; 5. Effective control of hypertension (blood pressure 130-100 / 80-60mmhg); 6. Patients whose blood potassium is within the normal range; 7. 2.5g/24h >= 24h urinary protein >= 0.5g/24h; 8. Patients who sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients diagnosed as acute nephritis after infection or patients with renal damage due to essential hypertension; 2. In the past three months, western medicine glucocorticoid, immunosuppressant and Tripterygium wilfordii have been used in patients with chronic nephritis; 3. Pregnant or preparing pregnant and lactating women; 4. Patients with chronic nephritis not caused by primary kidney disease; 5. Patients who are known to be allergic to such drugs, patients with psychosis, and patients who cannot cooperate; 6. Patients who are participating in clinical trials of other drugs or who have participated in other clinical trials within 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tongue image;Pulse condition;physical examination;TCM syndrome integral; | — |
Countries
China
Contacts
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine