Skip to content

Clinical study on the prevention and treatment of colorectal adenoma by regulating intestinal microecology: a randomized double-blind controlled trial

Clinical study on the prevention and treatment of colorectal adenoma by regulating intestinal microecology

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2000003350
Enrollment
Unknown
Registered
2020-05-28
Start date
2020-05-28
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal adenoma

Interventions

Sponsors

Shuguang Hospital affillated with Shanghai University of TCM
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Adenoma was definitely diagnosed by pathology, and the patients were between 18 and 75 years old. 2. The TCM syndrome type was consistent with cold and wet stasis syndrome or dampness and heat accumulation syndrome. 3. Patients with no previous history of colorectal surgery, cholecystectomy, familial adenomatous polyposis or hereditary non-polyposis colorectal cancer, or inflammatory bowel disease; 4. Not taking antibiotics, immunosuppressive agents, hormones or other drugs within three months; 5. Those who ate a relatively stable diet and voluntarily signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. The patients have digestive tract diseases, metabolic diseases, cardiovascular diseases, immune diseases, liver diseases, neurological diseases and autoimmune diseases. 2. Regular long-term use of yogurt or probiotics (2-3 times/week for more than 6 months); 3. Pregnant and lactating women; 4. To be allergic to a drug in a Chinese medicine prescription; 5. Has participated in other clinical investigators; 6. The researcher considers it inappropriate to participate in this experiment.

Design outcomes

Primary

MeasureTime frame
recurrence rate;

Secondary

MeasureTime frame
Bacterial metabolites;Characteristics and pathological types of adenoma;Intestinal microbiota structure;

Countries

China

Contacts

Public ContactWang Yan

Shuguang Hospital affillated with Shanghai University of TCM

wangyan_sg@126.com+86 13671739986

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026