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A randomized, double-blind placebo-controlled trial for Zishen Yutai Pill for endometrial repair in patients after artificial abortion

A randomized, double-blind placebo-controlled trial for Zishen Yutai Pill for endometrial repair in patients after artificial abortion

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2000003334
Enrollment
Unknown
Registered
2020-05-24
Start date
2020-05-22
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometrial injury after artificial abortion

Interventions

Sponsors

Centre for Reproductive Medicine, Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 18 to 40 years; 2. The patients who were diagnosed as early intrauterine pregnancy and asked for termination of pregnancy and accepted abortion; 3. The number of previous abortion 1-3; 4. Menstrual cycle in the first three months of pregnancy, 25-35 days and 3-10 days; 5. Objects who have been healthy without contraindications; 6. Patients who voluntarily cooperate with observation and treatment and have signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients who used proprietary Chinese medicine and hormone within the past month; 2. Subjects with previous allergic history to the test drug; 3. Patients with poor general conditions and intolerable to surgery; 4. Patients with previous endocrine abnormalities, uterine organic lesions and reproductive system tumors; 5. Patients with genital malformation, tumor or acute genital inflammation (such as acute pelvic inflammation, acute vaginitis, etc.); 6. The disabled patients (blind, deaf, dumb, mental disorder, mental disorder, physical disability) and the mentally ill patients specified by law; 7. Patients whose body temperature was above 37.5 degree C twice before operation; 8. Patients who have had the previous uterine cleaning for more than 4 times; 9. Patients with severe hepatorenal insufficiency.

Design outcomes

Primary

MeasureTime frame
Endometrial thickness (mm);

Secondary

MeasureTime frame
Menstruating time (day);Serum estradiol levels;Endometrial morphology;Uterine spiral artery resistance index;Serum progesterone levels;Duration of menstruation (days);Menstrual cycle time (days);

Countries

China

Contacts

Public ContactXiang Wenpei

Centre for Reproductive Medicine, Tongji Medical College, Huazhong University of Science and Technology

wpxiang2010@gmail.com+86 13886166929

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026