Endometrial injury after artificial abortion
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 to 40 years; 2. The patients who were diagnosed as early intrauterine pregnancy and asked for termination of pregnancy and accepted abortion; 3. The number of previous abortion 1-3; 4. Menstrual cycle in the first three months of pregnancy, 25-35 days and 3-10 days; 5. Objects who have been healthy without contraindications; 6. Patients who voluntarily cooperate with observation and treatment and have signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients who used proprietary Chinese medicine and hormone within the past month; 2. Subjects with previous allergic history to the test drug; 3. Patients with poor general conditions and intolerable to surgery; 4. Patients with previous endocrine abnormalities, uterine organic lesions and reproductive system tumors; 5. Patients with genital malformation, tumor or acute genital inflammation (such as acute pelvic inflammation, acute vaginitis, etc.); 6. The disabled patients (blind, deaf, dumb, mental disorder, mental disorder, physical disability) and the mentally ill patients specified by law; 7. Patients whose body temperature was above 37.5 degree C twice before operation; 8. Patients who have had the previous uterine cleaning for more than 4 times; 9. Patients with severe hepatorenal insufficiency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Endometrial thickness (mm); | — |
Secondary
| Measure | Time frame |
|---|---|
| Menstruating time (day);Serum estradiol levels;Endometrial morphology;Uterine spiral artery resistance index;Serum progesterone levels;Duration of menstruation (days);Menstrual cycle time (days); | — |
Countries
China
Contacts
Centre for Reproductive Medicine, Tongji Medical College, Huazhong University of Science and Technology