constipation
Conditions
Interventions
sham acupuncture group:sham acupuncture
Sponsors
Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) Age between 18 and 65 years; (2) Meet the DSM-5 diagnosis of schizophrenia and use antipsychotic medicine within the past 3 months; (3) Meet the diagnosis of antipsychotic-related constipation; (4) The average number of complete spontaneous bowel movements (CSBMs) no more than 3 times per week during the 14-day baseline period; (5) Patients and their families participate voluntarily, sign an informed consent form and promise to cooperate with follow-up and related examinations.
Exclusion criteria
Exclusion criteria: (1) Patients with mental instability over the past 2 weeks as indicated by their attending psychiatrist; (2) Constipation caused by organic diseases, functional diseases or other causes other than antipsychotic drugs; (3) Patients with severe heart, brain, liver, kidney and other dysfunction; (4) Pregnant and lactating women; (5) Patients with a pacemaker, metal allergy, or severe fear of needles; (6) Patients using drugs to treat constipation (except emergency treatment)or using anticholinergic drugs within 2 weeks before the trial; (7) Patients receiving acupuncture treatment within the past 3 months; (8) Patients participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change from baseline of mean weekly CSBMs during treatment period; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient Assessment of Constipation Symptoms;Brief Psychiatric Rating Scale;Use of rescue medicine and other assistant methods;Adverse events;Overall CSBM Response rate;Blinding assessment;Straining level;Change from baseline of mean weekly CSBMs during follow-up period;Credibility and expectancy;Patient Assessment of Constipation Quality of life questionnaire;Change from baseline of mean weekly SBMs;Bristol Stool Form Scale; | — |
Countries
China
Contacts
Public ContactCunzhi Liu
School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine
Outcome results
None listed