Knee Osteoarthritis
Conditions
Sponsors
Guanghua Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
50 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria of patients with knee osteoarthritis 1. 50-70 years old; 2. It was diagnosed as osteoarthritis of knee joint and agreed to participate in this experiment; 3. All of them are right handed; 4. KL Level 2 or 3; 5. The pain time of knee joint is more than or equal to 3 months; 6. Agree and sign the informed consent. Inclusion criteria for healthy volunteers 1. Right handedness; 2. The age range is 50-70 years old; 3. No history of chronic pain; 4. In the past 1 month, he did not receive medication, physical therapy or massage therapy; 5. Understand the process of the study, agree and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients taking analgesics or anti-inflammatory analgesics within the past 1 month; 2. Patients who received any other treatment within the past month; 3. Pregnant or lactating women; 4. Patients with mental disease, neurological disease, infectious disease, gastrointestinal disease, cardiovascular and cerebrovascular disease, immunologic disease, respiratory disease or kidney disease; 5. Patients with tumor, tuberculosis, rheumatism or rheumatoid arthritis, gout, joint trauma, or any other chronic pain symptoms, or with a history of brain injury with loss of consciousness; 6. Patients with MRI contraindications such as atresia phobia, pacemaker, defibrillator, cardiac stent, intrauterine device, etc..
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MRI scan to obtain various modal parameters; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pressure Pain Thresholds;Hamilton Depression Rating Scale; | — |
Countries
China
Contacts
Public ContactXiao Lianbo
Guanghua Integrated Chinese and Western Medicine Hospital Affiliated to Shanghai University of traditional Chinese Medicine
Outcome results
None listed