Subthreshold depression
Conditions
Interventions
Sponsors
Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients who meet the diagnostic criteria of depression under the threshold of Western medicine; Diagnosis standard of subthreshold depression: it has symptoms of depression, but fails to meet the symptom indicators required for diagnosis of depression (more than 5 of 9 items: loss of interest, no pleasure; energy loss or fatigue; psychomotor retardation or agitation; low self-evaluation, self blame, or guilt; difficulty in association or reduction of conscious thinking ability; recurrent thoughts of dying or having self Killing and self injuring behaviors; sleep disorders, such as insomnia, early wake-up, or excessive sleep; loss of appetite or weight; hyposexual desire) or course indicators (duration greater than 2 weeks). 2. The patients with CES-D score >= 16; 3. Hamilton Depression Scale (HAMD-17) score: 7 points <= HAMD total score < 17 points; 4. The patients with qi stagnation as the main constitution were classified and judged by the constitution of traditional Chinese medicine; 5. Patients aged over 18 and under 65, regardless of gender; 6. Patients who can independently complete the questionnaire, use the app, have informed consent and voluntarily fill in the questionnaire; Only those who meet the above six criteria can be selected into the research group.
Exclusion criteria
Exclusion criteria: 1. Patients with clinically confirmed depression, previous mental illness or organic mental disorder; 2. Patients with serious liver and kidney function damage, serious heart rate disorder or cardiac insufficiency; 3. Pregnancy, lactation and objects with pregnancy plan; 4. Patients with depressive episode caused by psychoactive substance and non addictive substance; 5. Patients who used other drugs or therapies to treat depression at the same time during the trial; 6. Known targets of drinking or substance dependence; 7. Patients with strong suicide attempt or behavior; 8. Patients who are participating in other clinical trials; 9. Those who fail to treat according to the specified requirements, fail to judge the curative effect or incomplete data that affect the judgment of curative effect or safety; 10. Patients who had received antidepressant treatment within one week before the trial. Those with one of the above items will not be included in the test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CES-D; | — |
Secondary
| Measure | Time frame |
|---|---|
| HAMD;Constitution scale score;PHQ-9; | — |
Countries
China
Contacts
Public ContactHan Zhenyun
Shenzhen Hospital of Beijing University of Chinese Medicine (Long Gang)
Outcome results
None listed