Non-small cell lung cancer
Conditions
Interventions
Sponsors
Shanghai Pulmonary Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients with locally advanced non-small cell lung cancer confirmed by pathology, who are not suitable for surgery and can accept radiotherapy and chemotherapy; 2. Patients aged 18-70 years old with ECoG PS 0-1 and expected survival time >=6 months; 3. For patients without major organ dysfunction and with basically normal heart, liver and kidney functions, the test indexes meet the following requirements: blood: leukocyte >4.0x10^9/L, neutrophil absolute value > 1.5x10^9/L, platelet count >100x10^9/L, hemoglobin >110g/L; liver function: serum bilirubin is 1.5 times lower than the maximum normal value; ALT and AST are 1.5 times lower than the maximum normal value; bun. Cr is within the normal range; 4. Pulmonary function: FEV1 >45%, DLCO >60% before treatment; 5. Patients without other cancers except stage I cervical cancer and skin basal cell carcinoma; 6. Patients with good compliance who can understand the situation of this study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with any acute or chronic diseases that are not suitable for radiotherapy and chemotherapy; 2. Patients with previous cancer history other than stage I cervical cancer and skin basal cell carcinoma, or who have undergone lobectomy or pneumonectomy; 3. Patients with active systemic infection or pulmonary or pericardial infection; 4. Pregnant or lactating women; 5. Patients with poor compliance with the protocol are not suitable for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| adverse effects; | — |
Countries
China
Contacts
Public ContactYaping Xu
Shanghai Pulmonary Hospital?
Outcome results
None listed