coronary heart disease
Conditions
Sponsors
Oriental Hospital, Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Consistent with the diagnosis of coronary heart disease angina pectoris, with one of the following evidence: (1) There is a clear history of old myocardial infarction; (2) Coronary angiography, suggesting at least one coronary stenosis, and lumen stenosis >=50%; (3) CTA suggested stenosis of the main vascular lumen >= 50% (or above moderate stenosis); 2. Angina pectoris attacks >=2 times per week; 3. Meet the diagnostic criteria of qi deficiency and blood stasis; 4. Aged 30-75 years; 5. Voluntarily sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Coronary revascularization was performed within 60 days; 2. Use any preparation of traditional Chinese medicine (such as proprietary Chinese medicine, Chinese medicine granule, etc.) in the recent month; 3. Acute myocardial infarction occurred in recent month; 4. Patients with one of the following diseases: (1) Patients with high blood pressure after hypertension and antihypertensive drug treatment (systolic blood pressure >= 180mmHg, diastolic blood pressure >=100mmHg); (2) Severe arrhythmia (atrial fibrillation with rapid ventricular response, atrial flutter, paroxysmal ventricular tachycardia, etc.), pulmonary heart disease, rheumatic heart disease, myocarditis, cardiomyopathy, aortic dissection, pulmonary embolism and other serious diseases; 5. Chest pain symptoms related to hyperthyroidism, cervical spondylosis, gallbladder heart syndrome, gastroesophageal reflux disease or hiatal hernia, neurosis, climacteric syndrome, etc.; 6. The upper limit of serum alanine transaminase or serum creatinine >2 times the normal reference value. 7. Severe hematological diseases. 8. Malignant tumor; 9. Women of child-bearing age who are pregnant or breast-feeding or who are required to have children; 10. Mental illness or cognitive dysfunction; 11. Allergic to the test drug; 12. Have participated in other clinical trials within the recent month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| response rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| ECG;TCM score;TCM symptom score;Seattle Angina Questionnaire;Sf-36 quality of life scale;Angina score scale; | — |
Countries
China
Contacts
Public ContactCui Xiaoyun
Oriental Hospital, Beijing University of Chinese Medicine
Outcome results
None listed