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Based on biomass spectrometry, the characteristics of n-glycosylation modification of salivary amylase in the dynamic evolution of spleen deficiency syndrome were studied

Based on biomass spectrometry, the characteristics of n-glycosylation modification of salivary amylase in the dynamic evolution of spleen deficiency syndrome were studied

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2000002892
Enrollment
Unknown
Registered
2020-01-03
Start date
2019-12-20
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes

Interventions

Case series:None

Sponsors

The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1. IGT and T2DM were diagnosed according to the diagnostic criteria of the American diabetes association in 2017; 2. Abdominal distension after eating; 3. Thin stool; 4. drink incense; 5. Fat tongue with tooth marks; 6. Weak pulse; Have binomial diagnosable. Diagnostic criteria for dampness and heat syndrome of spleen and stomach: 1. Abdominal distension; 2. thirsty drink less; 3. stay disgusted; 4. Heavy head; 5. yellow tongue coating greasy; 6. Pulse slip number; Have binomial diagnosable. Those meeting the above diagnostic criteria; Aged 18-65 years; Hemoglobin a1c (HbAlc) is less than or equal to 9%; Signed informed consent.

Exclusion criteria

Exclusion criteria: Failing to meet the diagnostic criteria; Type 1 diabetes mellitus, and T1DM with significant complications; Complicated with liver, kidney cardiovascular system, hematopoietic system, endocrine system and other serious primary diseases; Taking glucocorticoids and other drugs that have a greater effect on blood glucose; In the past two weeks, patients with mental diseases who take drugs that affect salivary secretion (such as anticholinergic drugs and anticholinesterase drugs, etc.) have no self-knowledge and cannot express accurately

Design outcomes

Primary

MeasureTime frame
biomass spectrometry;

Contacts

Public ContactLin Chuanquan
chuanquanlin@gzucm.edu.cn+86 15913117395

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026