primary biliary cirrhosis
Conditions
Interventions
Sponsors
Longhua Hospital, Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) signing the informed consent; (2) male or female aged 18-65 years; (3) the syndrome differentiation of traditional Chinese medicine is liver kidney yin deficiency, blood stasis blocking collaterals; (4) patients whose clinical diagnosis of Western medicine conforms to the PBC diagnostic standard and belongs to stage II and III;
Exclusion criteria
Exclusion criteria: (1) Combined with drug-induced liver injury, autoimmune hepatitis A, B, C, e, etc.; (2) patients with serious primary diseases of heart, brain, kidney, lung, endocrine, blood, metabolism and gastrointestinal tract, or psychosis; (3) creatinine (CR) is higher than the upper limit of normal value; (4) those who use drugs to lose weight; (5) an alcoholic or drug addict; (6) pregnant women, lactating women or those who prepare for pregnancy in the near future and those who use estrogen for contraception; (7) those who are allergic to a variety of drugs, this medicine or its components; (8) the patient is in critical condition, and it is difficult to make accurate evaluation on the effectiveness and safety of the new drug; (9) patients are not willing to cooperate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AMA;APRI;AMA-M2;Clinical symptom score ;Clinical efficiency;GLOBE-Score;Fibrotouch;Four items of liver fibrosis ;liver function; | — |
Countries
China
Contacts
Public ContactXing Lianjun
Longhua Hospital, Shanghai University of Traditional Chinese Medicine
Outcome results
None listed