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Study for the clinical effect and mechanism of Tong-Tian oral liquid versus bilirzattristan in the treatment of acute attack of chronic migraine

Study for the clinical effect and mechanism of Tong-Tian oral liquid versus bilirzattristan in the treatment of acute attack of chronic migraine

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR1900002873
Enrollment
Unknown
Registered
2019-12-27
Start date
2019-12-10
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic migraine

Interventions

Sponsors

Affiliated Hospital of Chengdu University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: 1. Meet the ichd-3beta diagnostic criteria issued by the international headache society (IHS) in 2018; 2. CT or MRI of the skull was normal, with neurologic examination (-); 3. Aged 18-55 years; 4. Those who are aware of the study and voluntarily sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with otogenic vertigo, cervical vertigo, vertigo epilepsy, multiple sclerosis, stroke, cardiovascular disease, diabetes, obesity and other metabolic disorders; 2. Patients with recent infection and other inflammatory reactions; 3. Patients who have taken traditional Chinese medicine for pain relief or proprietary Chinese medicine for nearly 2 weeks, those who have taken short-acting painkillers (except traditional Chinese medicine and proprietary Chinese medicine) for less than 5 half-lives, and those who have taken vitamin B supplements for nearly 1 month; 4. Patients with other organic diseases and tumors; Patients with diet and malnutrition and perinatal women.

Design outcomes

Primary

MeasureTime frame
VEGF;CGRP;Liver function;NO;DIC;SP;The pupil parameters;5-HT;6/5000 Common carotid artery diameter;Renal function;Diffusion tensor NMR imaging;Electrocardiogram, ECG;Ang;Routine blood;ET-1;

Countries

China

Contacts

Public ContactShi Min
175575128@qq.com+86 18280469975

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026