Skip to content

Brain network mechanism of modified Shaoyaogancao Decoction in the improvement of refractive asthenopia based on fMRI

Brain network mechanism of jiaweishaoyaogancao Decoction in the improvement of refractive asthenopia based on fMRI

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR1900002847
Enrollment
Unknown
Registered
2019-12-18
Start date
2020-01-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Refractive asthenopia

Interventions

Experimental group:modified Shaoyaogancao Decoction
Control group:placebo

Sponsors

Shuguang Hospital affiliated with Shanghai University of TCM
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) aged 18-40 years; (2) right handedness; (3) the main visual eye of the right eye was examined by the card hole method; (4) visual fatigue scale score > = 16 (professional version of visual fatigue scale of Wenzhou Medical University); (5) Meet the second edition of Wang Guangji's binocular vision; (6) the examination of ophthalmic biological parameters and visual function parameters confirmed the regulation of spasm; (7) presence of physical and mental symptoms: SAS score >50, SDS score >53, body factor score >1.37 + 0.48 in SCL-90; (8) understand the experimental process of this study and sign the informed consent.

Exclusion criteria

Exclusion criteria: (1) pregnant and lactating women; (2) patients with major organ dysfunction; (3) patients with acute conjunctivitis, keratopathy and other infectious eye diseases; (4) glaucoma and severe dry eye; (5) patients with a history of eye surgery within 1 month; (6) poor compliance; (7) patients who could not express the symptoms of ocular discomfort clearly and patients who could not understand the experimental process.

Design outcomes

Primary

MeasureTime frame
accommodative function of ciliary muscle;Visual fatigue scale integration;

Secondary

MeasureTime frame
Score of anxiety self rating scale;Score of depression self rating scale;Symptom Checklist-90;

Countries

China

Contacts

Public ContactTao Jin-hua
jinhuatao@hotmail.com+86 18601755691

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026