Subthreshold Depression
Conditions
Interventions
Sponsors
Fujian University of Traditional Chinese Medicine, Fuzhou, China
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The Center for Epidemiologic Studies Depression Scale (CES-D) score >=16; 2. According to the Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) (DSM-V), the Class A diagnostic criteria for major depressive disorder, met in the last two weeks. More than two and five or fewer participants; 3. Aged 18 to 44 years old, volunteers have a clear sense of consciousness; 4. Has not received any treatment for depression in the past 6 months; 5. In the past six months, he has not engaged in regular exercise (that is, at least 3 times a week, 20 minutes of regular exercise in various forms); 6. No MR examination contraindications; 7. Written informed consent.
Exclusion criteria
Exclusion criteria: 1. According to the "Diagnostic and Statistical Manual of Mental Disorders" (Fifth Edition) (DSM-V) criteria, to meet the diagnostic criteria for major depression, bipolar depression, and mental illness; 2. Has a history of major depression in the past 6 months; 3. Recent bereavement; 4. In the use of glucocorticoid drugs,psychotropic drugs or addiction disorders, such as the history of drug abuse and dependence and alcoholism; 5. Suffering from endocrine and metabolic diseases (Cushing's syndrome ,etc.); 6. Have a history of head trauma or a history of serious diseases such as heart, liver and kidney; 7. Pregnant women and lactating women; 8. Other clinical trials who are participating in the evaluation of the results of this study are participating.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The 17-item Hamilton Depression Scale (HAMD-17);9-item Patient Health Questionnaire, PHQ-9; | — |
Secondary
| Measure | Time frame |
|---|---|
| Center of Epidemiological Studies Depression Scale, CES-D;A 7-item Generalized Anxiety Disorder Assessment, GAD-7;Functional magnetic resonance imaging, fMRI;Chinese 14-item perceived stress scale, CPSS;Pittsburgh sleep quality index, PSQI; | — |
Countries
China
Contacts
Public ContactWu Jingsong
Outcome results
None listed