Infertile patients with advanced age and low prognosis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: In this study, we will recruit subjects who are 35 and 42 years old, meet the diagnostic criteria of western medicine infertility, insufficient ovarian reserve parameters (AFC = 10IU / L), poor ovarian response (i.e. oocytes obtained after standard ovarian stimulation <= 3), and meet the indications of IVF-ET.
Exclusion criteria
Exclusion criteria: (1) BMI >= 25Kg/m2; (2) those suffering from genetic diseases that are not suitable for reproduction as stipulated in the law on maternal and child health care; (3) severe endometriosis, adenomyosis, and immune infertility; (4) untreated hydrosalpinx; (5) congenital or acquired abnormal uterine development and other serious reproductive organ malformations; (6) complicated with reproductive system tumor, thyroid dysfunction, hyperprolactinemia and other endocrine dysfunction; (7) received ovarian stimulation treatment or OCP in recent 3 months; (8) no previous history of ovarian and other gynecological operations; (9) male factors (oligoweak teratozoospermia, obstructive azozoospermia, occult spermatozoospermia, etc.); (10) and other contraindications of assisted reproductive technology.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Obtain the number of follicles; | — |
Countries
China