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The effect and mechanism of Si-Jun-Zi decoction on the function of intestinal mucosal barrier during chemotherapy for colorectal cancer

The effect and mechanism of Si-Jun-Zi decoction on the function of intestinal mucosal barrier during chemotherapy for colorectal cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR1900002838
Enrollment
Unknown
Registered
2019-12-15
Start date
2019-12-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

Sponsors

Putuo Hospital, Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. have no chemotherapy, containing 5-Fu adjuvant chemotherapy, can complete the above plan course of high-risk stage II, III postoperative patients with colorectal cancer; 2. syndrome characteristics in line with the above TCM diagnostic criteria; 3. Aged 18-80 years; 4. Pg-sga <=8 points; 5. WHO PS score 0 to 1; 6. with normal liver and kidney function.

Exclusion criteria

Exclusion criteria: (1) mental patients and delirium, unable to communicate with the language of patients; (2) there are serious liver, kidney, heart and brain organs organic or functional lesions; (3) pregnant and nursing women; (4) Patients with definite other intestinal diseases in the recent 3 months; (5) In recent 3 months, patients who took drugs related to intestinal barrier function protection.

Design outcomes

Primary

MeasureTime frame
Intestinal barrier function;

Secondary

MeasureTime frame
TCM syndrome information;Nutritional status;intestinal flora;immune state;

Contacts

Public ContactTeng Chen
chenteng3387@126.com+86 13801842406

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026