Postoperative Delirium
Conditions
Interventions
Sponsors
The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Scheduled or limited for cardiac valve replacement with Cardiopulmonary acupuncture bypass patients aged 40 to 75 years old; 2. ASA I-III; 3. First thoracotomy; 4. Signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Suffered from the contraindication of TEAS including the local skin breakage, infection or planted with the electrophysiology device; 2. Unable to communicate and coordinate with the researcher, such as suffering from language comprehension deficits or mental diseases; 3. Certain/suspicious addiction with alcohol, analgenics or other drugs; 4. Preoperative placed intra-aortic balloon pump or ventricular assist device; 5. Severe dysfunction of liver or kidney meaning one of ALT, AST, ALP or TBIL is 2 times higher that normal or creatinine clearance 177umol/L; 6. Non-first-time thoracotomy; 7. Emergency surgery; 8. Participate in the other clinical trial 3 month before the enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Delirium scale (CAM-CR) score; | — |
Secondary
| Measure | Time frame |
|---|---|
| the expression of interleukin 17a (IL-17A) in serum;the expression of S100 beta protein in serum; | — |
Countries
China
Contacts
Public ContactBin Jia
The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
Outcome results
None listed