refractory asthma
Conditions
Interventions
Sponsors
Hospital of Chengdu University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Agde 18-65 years men or women, diagnosis of bronchial asthma for at least 1 year; 2. Patients conform to the diagnostic criteria of Western medicine refractory asthma; 3. Patients conform to the diagnostic standard of Chinese medicine asthma "External Cold and Internal Fluid Syndrome"; 4. Patients own good ability to read, understand and write research-related materials and comply with all trail requirements on a voluntary basis; 5. Patients voluntarily participate in research and sign informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients have a respiratory infection within 4 weeks; 2. Patients with chronic lung diseases require intervention or treatment such as chronic obstructive pulmonary disease, interstitial lung disease, active tuberculosis, bronchial dilation ; 3. Patients with serious primary diseases such as severe mental and psychological disorders, heart and brain vessels diseases, liver and kidney diseases, endocrine diseases, hematopoietic system diseases and malignant tumors ; 4. Patients take antibiotics within 3 months and eat yogurt or probiotics within 1 month; ? 5. Patients are unwilling or unable to change the current treatment plan; 6. Patients are known to be allergic to trail drugs or a certain Chinese medicine of this study; 7. Women are breastfeeding, pregnant or preparing for pregnancy; 8. Patients have more than 15 packs per year of smoking history ; 9. Patients have participated in other clinical studies in the past six months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Asthma Control Test(ACT) score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulmonary function(FEV1, FEV1/FVC, daytime and night peak expiratory flow(PEF));Average daily use of drugs that relieve asthma;Curative effect of TCM syndrome;Asthma Quality of Life Questionnaire(AQLQ);Changes in the composition of intestinal flora in the faeces of subjects; | — |
Countries
China
Contacts
Public ContactQingsong Huang
Hospital of Chengdu University of Traditional Chinese Medicine
Outcome results
None listed