chronic kidney disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meet the Western medicine diagnosis standard of high risk population with hepatitis B cirrhosis complicated with CKD; 2. Men or women aged 18-65; 3. Meet the syndrome of traditional Chinese medicine belongs to Yin deficiency of liver and kidney, Qi deficiency and blood stasis. 4. Sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Those who are allergy to the applied components of traditional Chinese medicine; 2. The researchers determined that antiviral treatment should be carried out while the patients themselves did not; 3. Cirrhosis with AKI or HRS; 4. Patients with other hepatophilic virus infection or with autoimmune liver disease, primary biliary cirrhosis, hereditary metabolic liver disease, unrequited alcoholic liver disease and liver transplantation; 5. Uncontrolled hypertension, diabetes, malignant tumor and other serious diseases; 6. Previous renal calculus, chronic glomerulonephritis, nephrotic syndrome, IgA nephropathy, systemic lupus erythematosus, nephrotoxic drug-related renal damage and other kidney diseases; 7. Baseline GFR < 60 ml / (min / 1.73 m2); 8. Women within pregnancy and lactation period; 9. Patients who cannot cooperate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of CKD; | — |
Secondary
| Measure | Time frame |
|---|---|
| Child Pugh and MELD scores;Incidence of hepatorenal syndrome;TCM syndrome scores; | — |
Countries
China
Contacts
Beijing Ditan Hospital, Capital Medical University